Скрининг на наследственные заболевания Экспертный

По статистике, каждый человек является носителем нескольких патогенных мутаций, которые могут передаваться из поколения в поколение и не вызывают клинических проявлений до тех пор, пока не появится ряд условий, способствующих обнаружению генетического заболевания. Для большинства наследственных заболеваний таким условием является зачатие ребенка носителями мутации в одном и том же гене — вероятность наличия у него патологии составляет 25%.

Исследование выполняется на базе полного секвенирования экзома и включает анализ кодирующих участков всех клинически значимых генов. В результате определяются как описанные патогенные и вероятно патогенные варианты, так и ранее неизвестныеde novo варианты классифицированные как патогенные/вероятно-патогенные по формальным критериям ACMG.

Кроме того, в исследование включен анализ числа копий гена SMN1, включая скрытое носительство. Потеря участков или всего гена SMN1 на отцовской и материнской хромосомах приводит к рождению ребенка с тяжелым заболеванием – спинальной мышечной атрофией.

Обладая информацией о носительстве мутаций, появляется возможность избежать появления ребенка с отклонением от нормы. Необходимые сведения можно получить с помощью скрининга на наследственные заболевания «Экспертный». В случае наличия патогенной мутации врач-генетик оценивает степень риска рождения ребенка с патологией, рассказывает о прогнозах и дает рекомендации по планированию беременности.

Скрининг «Экспертный» выявляет

• Носительство аутосомно-рецессивных заболеваний.
• Носительство наследственных заболеваний, сцепленных с Х-хромосомой.
• Доминантные мутации, характерные для наследственных болезней с поздней манифестацией.
• Мутации, связанные с онкологическими заболеваниями.

Исследование включает в себя анализ генетических вариантов клинически значимых генах, в том числе носительство спинальной мышечной атрофии (выявление делеции 7-8 экзонов гена SMN1).

Определяется широкий спектр наследственных заболеваний: тугоухость, наследственные нарушения обмена веществ (муковисцидоз, фенилкетонурия, галактоземия, болезнь Гоше, мукополисахаридозы и др.), неврологические наследственные заболевания (нервно-мышечные, наследственные эпилепсии, умственная отсталость), наследственные болезни сердца и др.

С помощью данного теста удается провести пресимптоматическую диагностику, которая является принципиально новой возможностью, позволяющей в ряде случаев осуществлять эффективное превентивное лечение (например, при болезни Вильсона-Коновалова). Но даже при отсутствии эффективного лечения информация о наличии или отсутствии патологического гена для членов семей со случаями наследственного заболевания имеет большое значение и служит важнейшим фактором для принятия многих жизненно важных решений, связанных с планированием семьи и деторождения, выбором работы и т.д.

Показания

• Кровнородственный брак.
• Наличие в семье ребенка или родственника с подозрением на наследственное заболевание.
• Донорство половых клеток.
• Планирование беременности.

По результатам исследования Вы получаете заключение врача-генетика.

Гены, что входят в скрининг

AAAS, AAGAB, AARS1, AARS2, AASS, ABAT, ABCA1, ABCA12, ABCA2, ABCA3, ABCA4, ABCB11, ABCB4, ABCB6, ABCB7, ABCC2, ABCC6, ABCC8, ABCC9, ABCD1, ABCD4, ABCG5, ABCG8, ABHD12, ABHD5, ABL1, ACAD8, ACAD9, ACADM, ACADS, ACADSB, ACADVL, ACAN, ACAT1, ACD, ACE, ACER3, ACO2, ACOX1, ACOX2, ACP4, ACP5, ACSF3, ACSL4, ACTA1, ACTA2, ACTB, ACTC1, ACTG1, ACTG2, ACTL6B, ACTN1, ACTN2, ACTN4, ACVR1, ACVR2B, ACVRL1, ACY1, ADA, ADA2, ADAM10, ADAM17, ADAM22, ADAM9, ADAMTS10, ADAMTS13, ADAMTS17, ADAMTS18, ADAMTS2, ADAMTS3, ADAMTSL2, ADAMTSL4, ADAR, ADAT3, ADCY5, ADCY6, ADD3, ADGRE2, ADGRG1, ADGRG2, ADGRG6, ADGRV1, ADK, ADNP, ADPRS, ADSL, ADSS1, AEBP1, AFF2, AFF4, AFG3L2, AGA, AGBL1, AGBL5, AGK, AGL, AGPAT2, AGPS, AGRN, AGT, AGTPBP1, AGTR1, AGXT, AHCY, AHDC1, AHI1, AHR, AHSG, AICDA, AIFM1, AIMP1, AIP, AIPL1, AIRE, AK1, AK2, AK7, AKAP9, AKR1C2, AKR1D1, AKT1, AKT2, AKT3, ALAD, ALAS2, ALB, ALDH18A1, ALDH1A3, ALDH3A2, ALDH4A1, ALDH5A1, ALDH6A1, ALDH7A1, ALDOA, ALDOB, ALG1, ALG11, ALG12, ALG13, ALG14, ALG2, ALG3, ALG6, ALG8, ALG9, ALKBH8, ALMS1, ALOX12B, ALOXE3, ALPK3, ALPL, ALS2, ALX1, ALX3, ALX4, AMACR, AMBN, AMELX, AMER1, AMH, AMHR2, AMMECR1, AMN, AMPD1, AMPD2, AMT, ANAPC1, ANGPTL3, ANK1, ANK2, ANK3, ANKH, ANKLE2, ANKRD11, ANKRD26, ANKS6, ANLN, ANO10, ANO3, ANO5, ANO6, ANOS1, ANTXR1, ANTXR2, ANXA11, AP1B1, AP1S1, AP1S2, AP2M1, AP2S1, AP3B1, AP3B2, AP3D1, AP4B1, AP4E1, AP4M1, AP4S1, AP5Z1, APC, APC2, APCDD1, APOA1, APOA5, APOB, APOC2, APOC3, APOE, APP, APRT, APTX, AQP2, AQP5, AR, ARCN1, ARF1, ARFGEF2, ARG1, ARHGAP31, ARHGDIA, ARHGEF1, ARHGEF10, ARHGEF18, ARHGEF9, ARID1A, ARID1B, ARID2, ARL13B, ARL2BP, ARL3, ARL6, ARL6IP1, ARMC2, ARMC4, ARMC5, ARMC9, ARNT2, ARPC1B, ARR3, ARSA, ARSB, ARSG, ARSL, ARV1, ARX, ASAH1, ASB10, ASCC1, ASCL1, ASH1L, ASL, ASNS, ASPA, ASPH, ASPM, ASS1, ASXL1, ASXL2, ASXL3, ATAD1, ATAD3A, ATF6, ATIC, ATL1, ATL3, ATM, ATN1, ATOH7, ATP13A2, ATP1A1, ATP1A2, ATP1A3, ATP2A1, ATP2A2, ATP2B2, ATP2B3, ATP2C1, ATP5F1A, ATP5F1D, ATP5F1E, ATP5MD, ATP6AP1, ATP6AP2, ATP6V0A2, ATP6V0A4, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP7A, ATP7B, ATP8A2, ATP8B1, ATPAF2, ATR, ATRX, ATXN1, ATXN2, ATXN3, ATXN7, AUH, AURKC, AUTS2, AVIL, AVP, AVPR2, AXIN2, B2M, B3GALNT2, B3GALT6, B3GAT3, B3GLCT, B4GALNT1, B4GALT1, B4GALT7, B4GAT1, B9D1, B9D2, BAAT, BACH2, BAG3, BANF1, BAP1, BARD1, BBIP1, BBS1, BBS10, BBS12, BBS2, BBS4, BBS5, BBS7, BBS9, BCAP31, BCHE, BCKDHA, BCKDHB, BCKDK, BCL10, BCL11A, BCL11B, BCO1, BCOR, BCORL1, BCS1L, BDP1, BEST1, BFSP1, BFSP2, BGN, BHLHA9, BICD2, BIN1, BLK, BLM, BLNK, BLOC1S3, BLOC1S6, BLVRA, BMP1, BMP15, BMP2, BMP4, BMPER, BMPR1A, BMPR1B, BMPR2, BMS1, BNC1, BNC2, BOLA3, BPGM, BPNT2, BPTF, BRAF, BRAT1, BRCA1, BRCA2, BRF1, BRIP1, BRPF1, BRWD3, BSCL2, BSND, BTD, BTK, BUB1B, BVES, C11orf80, C12orf4, C12orf57, C12orf65, C19orf12, C1QA, C1QB, C1QBP, C1QC, C1QTNF5, C1R, C1S, C2, C2CD3, C3, C5, C6, C7, C8B, C8orf37, C9, C9orf72, CA12, CA2, CA4, CA5A, CA8, CABP4, CACNA1A, CACNA1B, CACNA1C, CACNA1D, CACNA1E, CACNA1F, CACNA1G, CACNA1H, CACNA1S, CACNA2D2, CACNA2D4, CACNB2, CACNB4, CAD, CALM1, CALM2, CALM3, CAMK2A, CAMK2B, CAMTA1, CANT1, CAPN1, CAPN3, CAPN5, CARD11, CARD14, CARD9, CARMIL2, CARS2, CASK, CASP10, CASQ1, CASQ2, CASR, CAST, CAT, CATSPER1, CAV1, CAV3, CAVIN1, CBL, CBLIF, CBS, CBX2, CC2D1A, CC2D2A, CCBE1, CCDC103, CCDC114, CCDC115, CCDC151, CCDC174, CCDC22, CCDC39, CCDC40, CCDC47, CCDC65, CCDC78, CCDC8, CCDC88A, CCDC88C, CCM2, CCN6, CCND2, CCNO, CCNQ, CD151, CD164, CD19, CD247, CD27, CD2AP, CD36, CD3D, CD3E, CD3G, CD40, CD40LG, CD46, CD55, CD59, CD70, CD79A, CD79B, CD81, CD8A, CD96, CDAN1, CDC14A, CDC42, CDC45, CDC6, CDC73, CDCA7, CDH1, CDH11, CDH23, CDH3, CDHR1, CDIN1, CDK10, CDK13, CDK5RAP2, CDK6, CDK8, CDKL5, CDKN1B, CDKN1C, CDKN2A, CDON, CDSN, CDT1, CEACAM16, CEBPE, CEL, CELA2A, CENPE, CENPF, CENPJ, CEP104, CEP120, CEP135, CEP152, CEP164, CEP19, CEP250, CEP290, CEP41, CEP55, CEP57, CEP63, CEP78, CEP83, CERKL, CERS3, CERT1, CES1, CFAP251, CFAP298, CFAP300, CFAP410, CFAP43, CFAP44, CFAP53, CFAP65, CFAP69, CFAP70, CFB, CFC1, CFD, CFH, CFHR5, CFI, CFL2, CFP, CFTR, CHAMP1, CHAT, CHCHD10, CHCHD2, CHD1, CHD2, CHD3, CHD4, CHD7, CHD8, CHEK2, CHKB, CHM, CHMP1A, CHMP2B, CHMP4B, CHN1, CHRDL1, CHRM3, CHRNA1, CHRNA2, CHRNA3, CHRNA4, CHRNB1, CHRNB2, CHRND, CHRNE, CHRNG, CHST14, CHST3, CHST6, CHSY1, CHUK, CIB2, CIC, CIDEC, CIITA, CILK1, CISD2, CIT, CITED2, CKAP2L, CLCF1, CLCN1, CLCN2, CLCN4, CLCN5, CLCN7, CLCNKA, CLCNKB, CLDN1, CLDN10, CLDN14, CLDN16, CLDN19, CLIC2, CLIC5, CLMP, CLN3, CLN5, CLN6, CLN8, CLP1, CLPB, CLPP, CLRN1, CLTC, CNGA1, CNGA3, CNGB1, CNGB3, CNKSR2, CNNM2, CNNM4, CNOT2, CNOT3, CNPY3, CNTN1, CNTN2, CNTNAP1, CNTNAP2, COA5, COA6, COA7, COA8, COASY, COCH, COG1, COG2, COG4, COG5, COG6, COG7, COG8, COL10A1, COL11A1, COL11A2, COL12A1, COL13A1, COL17A1, COL18A1, COL1A1, COL1A2, COL25A1, COL27A1, COL2A1, COL3A1, COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6, COL5A1, COL5A2, COL6A1, COL6A2, COL6A3, COL7A1, COL8A2, COL9A1, COL9A2, COL9A3, COLEC10, COLEC11, COLGALT1, COLQ, COMP, COPA, COPB2, COQ2, COQ4, COQ6, COQ8A, COQ8B, COQ9, CORIN, CORO1A, COX10, COX14, COX15, COX20, COX6A1, COX6A2, COX6B1, COX7B, COX8A, CP, CPA6, CPAMD8, CPLANE1, CPLX1, CPOX, CPS1, CPSF1, CPT1A, CPT1C, CPT2, CR2, CRADD, CRAT, CRB1, CRB2, CRBN, CREB3L1, CREBBP, CRELD1, CRIPT, CRLF1, CRPPA, CRTAP, CRX, CRYAA, CRYAB, CRYBA1, CRYBA4, CRYBB1, CRYBB2, CRYBB3, CRYGB, CRYGC, CRYGD, CRYGS, CRYM, CSF1R, CSF2RA, CSF2RB, CSF3R, CSNK1D, CSNK2A1, CSNK2B, CSPP1, CSRP3, CST3, CSTA, CSTB, CTC1, CTCF, CTH, CTHRC1, CTLA4, CTNNA1, CTNNA2, CTNNA3, CTNNB1, CTNND1, CTNS, CTPS1, CTSA, CTSC, CTSD, CTSF, CTSK, CTU2, CUBN, CUL3, CUL4B, CUL7, CUX1, CUX2, CWC27, CWF19L1, CXCR4, CXorf56, CYB561, CYB5A, CYB5R3, CYBA, CYBB, CYC1, CYCS, CYFIP2, CYLD, CYP11A1, CYP11B1, CYP11B2, CYP17A1, CYP19A1, CYP1B1, CYP21A2, CYP24A1, CYP26B1, CYP27A1, CYP27B1, CYP2R1, CYP2U1, CYP4F22, CYP4V2, CYP7B1, D2HGDH, DACT1, DAG1, DARS1, DARS2, DBH, DBT, DCAF17, DCAF8, DCC, DCDC2, DCHS1, DCLRE1C, DCN, DCPS, DCTN1, DCX, DDB2, DDC, DDHD1, DDHD2, DDOST, DDR2, DDRGK1, DDX11, DDX3X, DDX58, DDX59, DDX6, DEAF1, DEGS1, DENND5A, DEPDC5, DES, DGAT1, DGKE, DGUOK, DHCR24, DHCR7, DHDDS, DHFR, DHH, DHODH, DHTKD1, DHX16, DHX30, DHX37, DHX38, DIABLO, DIAPH1, DICER1, DIS3L2, DKC1, DLAT, DLD, DLG3, DLG4, DLL1, DLL3, DLL4, DLST, DLX3, DLX4, DLX5, DMD, DMGDH, DMP1, DMPK, DMXL2, DNA2, DNAAF1, DNAAF2, DNAAF3, DNAAF4, DNAAF5, DNAAF6, DNAH1, DNAH11, DNAH17, DNAH5, DNAH9, DNAI1, DNAI2, DNAJB11, DNAJB13, DNAJB2, DNAJB6, DNAJC12, DNAJC19, DNAJC21, DNAJC3, DNAJC5, DNAJC6, DNAL1, DNAL4, DNASE1L3, DNM1, DNM1L, DNM2, DNMBP, DNMT1, DNMT3A, DNMT3B, DOCK2, DOCK3, DOCK6, DOCK7, DOCK8, DOK7, DOLK, DONSON, DPAGT1, DPF2, DPH1, DPM1, DPM2, DPM3, DPP6, DPY19L2, DPYD, DPYS, DRAM2, DRC1, DSC2, DSC3, DSE, DSG1, DSG2, DSG4, DSP, DSPP, DST, DSTYK, DTNA, DTNBP1, DUOX2, DUOXA2, DUSP6, DVL1, DVL3, DYM, DYNC1H1, DYNC1I2, DYNC2H1, DYNC2I1, DYNC2I2, DYNC2LI1, DYRK1A, DYRK1B, DYSF, DZIP1L, EARS2, EBF3, EBP, ECE1, ECEL1, ECHS1, ECM1, EDA, EDAR, EDARADD, EDC3, EDN1, EDN3, EDNRA, EDNRB, EED, EEF1A2, EEF2, EFEMP1, EFEMP2, EFHC1, EFL1, EFNB1, EFTUD2, EGF, EGFR, EGLN1, EGR2, EHHADH, EHMT1, EIF2AK3, EIF2AK4, EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5, EIF2S3, EIF3F, EIF4A3, ELAC2, ELANE, ELMO2, ELMOD3, ELN, ELOVL1, ELOVL4, ELOVL5, ELP1, ELP2, ELP4, EMC1, EMD, EMG1, EML1, EMP2, EMX2, ENAM, ENG, ENO3, ENPP1, ENTPD1, EOGT, EP300, EPAS1, EPB41, EPB41L1, EPB42, EPCAM, EPG5, EPHA2, EPHB4, EPM2A, EPO, EPOR, EPRS1, EPS8, EPS8L2, EPS8L3, ERAL1, ERBB3, ERBB4, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, ERCC6L2, ERCC8, ERF, ERGIC1, ERLIN1, ERLIN2, ERMARD, ESCO2, ESPN, ESR1, ESRP1, ESRRB, ETFA, ETFB, ETFDH, ETHE1, ETV6, EVC, EVC2, EXOC6B, EXOSC2, EXOSC3, EXOSC8, EXOSC9, EXPH5, EXT1, EXT2, EXTL3, EYA1, EYA4, EYS, EZH2, F10, F11, F12, F13A1, F13B, F2, F5, F7, F8, F9, FA2H, FADD, FAH, FAM111A, FAM111B, FAM126A, FAM149B1, FAM161A, FAM20A, FAM20C, FAM83H, FAN1, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, FAR1, FARS2, FARSB, FAS, FASTKD2, FAT4, FBLN5, FBN1, FBN2, FBP1, FBXL3, FBXL4, FBXO11, FBXO31, FBXO38, FBXO7, FCSK, FDFT1, FDPS, FDX2, FDXR, FECH, FERMT1, FERMT3, FEZF1, FGA, FGB, FGD1, FGD4, FGF10, FGF12, FGF14, FGF16, FGF17, FGF20, FGF23, FGF3, FGF5, FGF8, FGF9, FGFR1, FGFR2, FGFR3, FGG, FH, FHL1, FIBP, FIG4, FIGLA, FITM2, FKBP10, FKBP14, FKRP, FKTN, FLAD1, FLCN, FLG, FLG2, FLI1, FLNA, FLNB, FLNC, FLRT3, FLT4, FLVCR1, FLVCR2, FMN2, FMO3, FMR1, FN1, FOLR1, FOXC1, FOXC2, FOXE1, FOXE3, FOXF1, FOXG1, FOXI1, FOXJ1, FOXL2, FOXN1, FOXP1, FOXP2, FOXP3, FOXRED1, FRAS1, FREM1, FREM2, FRMD4A, FRMD7, FRMPD4, FRRS1L, FSHB, FSHR, FSIP2, FTCD, FTL, FTO, FTSJ1, FUCA1, FUS, FUT1, FUT8, FXN, FXR1, FXYD2, FYB1, FYCO1, FZD2, FZD4, FZD6, G6PC, G6PC3, G6PD, GAA, GABBR2, GABRA1, GABRA2, GABRA5, GABRB1, GABRB2, GABRB3, GABRG2, GAD1, GAL, GALC, GALE, GALK1, GALNS, GALNT3, GALT, GAMT, GAN, GANAB, GARS1, GAS2L2, GAS8, GATA1, GATA2, GATA3, GATA4, GATA5, GATA6, GATAD1, GATAD2B, GATM, GBA, GBA2, GBE1, GCDH, GCH1, GCK, GCLC, GCM2, GCNT2, GCSH, GDAP1, GDAP2, GDF1, GDF2, GDF3, GDF5, GDF6, GDF9, GDI1, GEMIN4, GFAP, GFER, GFI1, GFI1B, GFM1, GFM2, GFPT1, GGCX, GH1, GHR, GHRHR, GHSR, GINS1, GIPC3, GJA1, GJA3, GJA5, GJA8, GJB1, GJB2, GJB3, GJB4, GJB6, GJC2, GK, GLA, GLB1, GLDC, GLDN, GLE1, GLI1, GLI2, GLI3, GLIS2, GLIS3, GLMN, GLRA1, GLRB, GLRX5, GLS, GLUD1, GLUL, GLYCTK, GM2A, GMNN, GMPPA, GMPPB, GNA11, GNAI2, GNAI3, GNAL, GNAO1, GNAQ, GNAS, GNAT1, GNAT2, GNB1, GNB3, GNB4, GNB5, GNE, GNMT, GNPAT, GNPTAB, GNPTG, GNRH1, GNRHR, GNS, GORAB, GOSR2, GOT2, GP1BA, GP1BB, GP6, GP9, GPAA1, GPC3, GPC4, GPC6, GPD1, GPHN, GPI, GPIHBP1, GPNMB, GPR143, GPR179, GPR68, GPRASP2, GPSM2, GPT2, GPX4, GRAP, GREB1L, GREM2, GRHL2, GRHL3, GRHPR, GRIA3, GRIA4, GRID2, GRIK2, GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIP1, GRK1, GRM1, GRM6, GRN, GRXCR1, GSC, GSDME, GSN, GSR, GSS, GSX2, GTF2E2, GTF2H5, GTPBP2, GTPBP3, GUCA1A, GUCY1A1, GUCY2C, GUCY2D, GUF1, GUSB, GYG1, GYS1, GYS2, GZF1, H1-4, H6PD, HAAO, HACE1, HADH, HADHA, HADHB, HAMP, HARS1, HARS2, HAX1, HBA1, HBA2, HBB, HBD, HBG2, HCCS, HCFC1, HCN1, HCN4, HDAC8, HECW2, HELLS, HEPACAM, HEPHL1, HERC1, HERC2, HES7, HESX1, HEXA, HEXB, HFE, HFM1, HGD, HGF, HGSNAT, HIBCH, HIKESHI, HINT1, HIVEP2, HJV, HK1, HLCS, HMBS, HMGCL, HMGCS2, HMOX1, HMX1, HNF1A, HNF1B, HNF4A, HNMT, HNRNPA1, HNRNPA2B1, HNRNPDL, HNRNPH2, HNRNPK, HNRNPU, HOGA1, HOMER2, HOXA1, HOXA11, HOXA13, HOXA2, HOXB1, HOXC13, HOXD10, HOXD13, HPCA, HPD, HPGD, HPRT1, HPS1, HPS3, HPS4, HPS5, HPS6, HPSE2, HR, HRAS, HRG, HSD11B1, HSD11B2, HSD17B10, HSD17B3, HSD17B4, HSD3B2, HSD3B7, HSF4, HSPA9, HSPB1, HSPB8, HSPD1, HSPG2, HTRA1, HTRA2, HTT, HUWE1, HYAL1, HYDIN, IARS1, IARS2, IBA57, ICOS, IDH2, IDH3B, IDS, IDUA, IER3IP1, IFIH1, IFITM5, IFNGR1, IFNGR2, IFT122, IFT140, IFT172, IFT27, IFT43, IFT52, IFT57, IFT80, IFT81, IGF1, IGF1R, IGF2, IGFALS, IGFBP7, IGHMBP2, IGLL1, IGSF1, IGSF3, IHH, IKBKB, IKBKG, IKZF1, IL10RA, IL10RB, IL11RA, IL12B, IL12RB1, IL17F, IL17RA, IL17RC, IL17RD, IL1RAPL1, IL1RN, IL21, IL21R, IL2RA, IL2RB, IL2RG, IL31RA, IL36RN, IL6ST, IL7R, ILDR1, IMPDH1, IMPG1, IMPG2, INF2, INPP5E, INPP5K, INPPL1, INS, INSL3, INSR, INTS1, INTS8, INTU, INVS, IQCB1, IQCE, IQSEC1, IQSEC2, IRAK4, IREB2, IRF2BP2, IRF2BPL, IRF6, IRF7, IRF8, IRS1, IRS4, IRX5, ISCA1, ISCA2, ISCU, ISG15, ITCH, ITGA2B, ITGA3, ITGA6, ITGA7, ITGA8, ITGB2, ITGB3, ITGB4, ITGB6, ITK, ITM2B, ITPA, ITPR1, ITPR2, IVD, IYD, JAG1, JAGN1, JAK2, JAK3, JAM2, JAM3, JPH2, JPH3, JUP, KANK1, KANK2, KANSL1, KARS1, KAT6A, KAT6B, KATNB1, KATNIP, KBTBD13, KCNA1, KCNA2, KCNA5, KCNB1, KCNC1, KCNC3, KCND3, KCNE1, KCNE2, KCNH1, KCNH2, KCNJ1, KCNJ10, KCNJ11, KCNJ13, KCNJ18, KCNJ2, KCNJ5, KCNJ6, KCNK3, KCNK4, KCNK9, KCNMA1, KCNN3, KCNN4, KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5, KCNT1, KCNT2, KCNV2, KCTD1, KCTD17, KCTD7, KDF1, KDM1A, KDM5B, KDM5C, KDM6A, KDSR, KERA, KHDC3L, KIAA0586, KIAA0753, KIAA0825, KIAA1109, KIAA1549, KIDINS220, KIF11, KIF14, KIF1A, KIF1B, KIF1C, KIF21A, KIF22, KIF2A, KIF4A, KIF5A, KIF5C, KIF7, KIFBP, KISS1, KISS1R, KIT, KITLG, KIZ, KLF1, KLF11, KLHL10, KLHL24, KLHL3, KLHL40, KLHL41, KLHL7, KLK4, KLKB1, KMT2A, KMT2B, KMT2C, KMT2D, KMT2E, KMT5B, KNL1, KPTN, KRAS, KRIT1, KRT1, KRT10, KRT12, KRT13, KRT14, KRT16, KRT17, KRT2, KRT25, KRT3, KRT4, KRT5, KRT6A, KRT6B, KRT6C, KRT71, KRT74, KRT81, KRT83, KRT85, KRT86, KRT9, KY, KYNU, L1CAM, L2HGDH, LACC1, LAGE3, LAMA1, LAMA2, LAMA3, LAMA4, LAMB1, LAMB2, LAMB3, LAMC2, LAMC3, LAMP2, LARGE1, LARP7, LARS1, LARS2, LAS1L, LAT, LBR, LCA5, LCAT, LCK, LCT, LDB3, LDHD, LDLR, LDLRAP1, LEMD2, LEMD3, LEP, LEPR, LFNG, LGI1, LGI4, LHB, LHCGR, LHFPL5, LHX3, LHX4, LIAS, LIFR, LIG4, LIM2, LIMS2, LINGO1, LINS1, LIPA, LIPC, LIPE, LIPH, LIPN, LIPT1, LIPT2, LITAF, LMAN1, LMAN2L, LMBRD1, LMF1, LMNA, LMNB2, LMOD3, LMX1A, LMX1B, LNPK, LONP1, LORICRIN, LOX, LOXHD1, LPAR6, LPIN1, LPIN2, LPL, LRAT, LRBA, LRIG2, LRIT3, LRMDA, LRP1, LRP2, LRP4, LRP5, LRP6, LRPAP1, LRPPRC, LRRC56, LRRC6, LRSAM1, LRTOMT, LSS, LTBP2, LTBP3, LTBP4, LYRM4, LYRM7, LYST, LYZ, LZTFL1, LZTR1, MAB21L1, MAB21L2, MACF1, MAD2L2, MAF, MAFB, MAG, MAGED2, MAGEL2, MAGI2, MAGT1, MAK, MALT1, MAMLD1, MAN1B1, MAN2B1, MANBA, MAOA, MAP11, MAP2K1, MAP2K2, MAP3K1, MAP3K20, MAP3K7, MAPK8IP3, MAPKAPK3, MAPKBP1, MAPRE2, MAPT, MARS1, MARS2, MARVELD2, MASP1, MAST1, MAT1A, MATN3, MATR3, MBD5, MBOAT7, MBTPS1, MBTPS2, MC2R, MC4R, MCCC1, MCCC2, MCEE, MCFD2, MCIDAS, MCM2, MCM3AP, MCM4, MCM5, MCM8, MCM9, MCOLN1, MCPH1, MDH2, MDM2, MECOM, MECP2, MECR, MED12, MED13, MED13L, MED17, MED23, MED25, MEF2C, MEFV, MEGF10, MEGF8, MEI1, MEIOB, MEIS2, MEN1, MEOX1, MERTK, MESD, MESP2, MET, METTL23, METTL5, MFAP5, MFF, MFN2, MFRP, MFSD2A, MFSD8, MGAT2, MGME1, MGP, MIB1, MICOS13, MICU1, MID1, MID2, MIP, MIPEP, MIR96, MITF, MKKS, MKRN3, MKS1, MLC1, MLH1, MLH3, MLPH, MLYCD, MMAA, MMAB, MMACHC, MMADHC, MME, MMP13, MMP14, MMP2, MMP20, MMP21, MMUT, MN1, MNX1, MOCOS, MOCS1, MOCS2, MOGS, MORC2, MPC1, MPDU1, MPDZ, MPI, MPIG6B, MPL, MPLKIP, MPO, MPV17, MPZ, MPZL2, MRAP, MRAS, MRE11, MRPL3, MRPL44, MRPS16, MRPS2, MRPS22, MRPS34, MRPS7, MSH2, MSH3, MSH6, MSL3, MSMO1, MSN, MSR1, MSRB3, MSTO1, MSX1, MSX2, MTFMT, MTHFD1, MTHFR, MTHFS, MTM1, MTMR2, MTO1, MTOR, MTPAP, MTR, MTRR, MTTP, MUSK, MUTYH, MVD, MVK, MYBPC1, MYBPC3, MYCN, MYD88, MYF5, MYH11, MYH14, MYH2, MYH3, MYH6, MYH7, MYH8, MYH9, MYL1, MYL2, MYL3, MYL4, MYLK, MYLK2, MYMK, MYO15A, MYO18B, MYO1E, MYO3A, MYO5A, MYO5B, MYO6, MYO7A, MYOC, MYOCD, MYORG, MYOT, MYOZ2, MYPN, MYRF, MYSM1, MYT1L, NAA10, NAA15, NACC1, NADK2, NAGA, NAGLU, NAGS, NALCN, NANOS1, NANS, NARS2, NAXD, NAXE, NBAS, NBEAL2, NBN, NCAPD2, NCAPD3, NCAPG2, NCF1, NCF2, NCF4, NCSTN, NDE1, NDNF, NDP, NDRG1, NDST1, NDUFA1, NDUFA10, NDUFA11, NDUFA12, NDUFA13, NDUFA2, NDUFA6, NDUFA9, NDUFAF1, NDUFAF2, NDUFAF3, NDUFAF4, NDUFAF5, NDUFAF6, NDUFAF8, NDUFB11, NDUFB3, NDUFB8, NDUFB9, NDUFS1, NDUFS2, NDUFS3, NDUFS4, NDUFS6, NDUFS7, NDUFS8, NDUFV1, NDUFV2, NEB, NECAP1, NECTIN1, NECTIN4, NEDD4L, NEFH, NEFL, NEK1, NEK10, NEK8, NEK9, NEU1, NEUROD1, NEUROD2, NEUROG3, NEXMIF, NEXN, NF1, NF2, NFASC, NFE2L2, NFIA, NFIB, NFIX, NFKB1, NFKB2, NFKBIA, NFU1, NGF, NGLY1, NHEJ1, NHLRC1, NHLRC2, NHS, NIN, NIPA1, NIPAL4, NIPBL, NKAP, NKX2-1, NKX2-5, NKX2-6, NKX3-2, NKX6-2, NLGN3, NLGN4X, NLRC4, NLRP1, NLRP12, NLRP3, NLRP7, NME8, NMNAT1, NNT, NOBOX, NOD2, NODAL, NOG, NOL3, NONO, NOP10, NOP56, NOTCH1, NOTCH2, NOTCH3, NPC1, NPC2, NPHP1, NPHP3, NPHP4, NPHS1, NPHS2, NPPA, NPR2, NPRL2, NPRL3, NR0B1, NR0B2, NR1H4, NR2E3, NR2F1, NR2F2, NR3C1, NR3C2, NR5A1, NRAS, NRL, NRXN1, NSD1, NSDHL, NSMCE2, NSMCE3, NSUN2, NT5C2, NT5C3A, NT5E, NTF4, NTHL1, NTN1, NTNG2, NTRK1, NTRK2, NUBPL, NUP107, NUP133, NUP155, NUP188, NUP205, NUP214, NUP37, NUP62, NUP85, NUP88, NUP93, NUS1, NXN, NYX, OAT, OBSL1, OCA2, OCLN, OCRL, ODAPH, OFD1, OGT, OPA1, OPA3, OPHN1, OPLAH, OPN1LW, OPN1MW, OPN1SW, OPTN, ORAI1, ORC1, ORC4, ORC6, OSBPL2, OSGEP, OSMR, OSTM1, OTC, OTOA, OTOF, OTOG, OTOGL, OTUD6B, OTULIN, OTX2, OXCT1, OXR1, P2RX2, P2RY12, P3H1, P3H2, P4HA2, P4HB, P4HTM, PABPN1, PACS1, PACS2, PADI3, PADI6, PAFAH1B1, PAH, PAK1, PAK3, PALB2, PAM16, PANK2, PANX1, PAPSS2, PARK7, PARN, PARS2, PATL2, PAX1, PAX2, PAX3, PAX4, PAX6, PAX7, PAX8, PAX9, PBX1, PC, PCARE, PCBD1, PCCA, PCCB, PCDH12, PCDH15, PCDH19, PCGF2, PCK1, PCK2, PCLO, PCNA, PCNT, PCSK1, PCSK9, PCYT1A, PCYT2, PDCD10, PDE10A, PDE11A, PDE1C, PDE3A, PDE4D, PDE6A, PDE6B, PDE6C, PDE6D, PDE6H, PDE8B, PDGFB, PDGFRA, PDGFRB, PDHA1, PDHB, PDHX, PDK3, PDP1, PDSS1, PDSS2, PDX1, PDXK, PDYN, PDZD7, PEPD, PER2, PER3, PET100, PEX1, PEX10, PEX11B, PEX12, PEX13, PEX14, PEX16, PEX19, PEX2, PEX26, PEX3, PEX5, PEX6, PEX7, PFKM, PFN1, PGAM2, PGAP1, PGAP2, PGAP3, PGK1, PGM1, PGM3, PHC1, PHEX, PHF21A, PHF6, PHF8, PHGDH, PHIP, PHKA1, PHKA2, PHKB, PHKG2, PHOX2A, PHOX2B, PHYH, PI4KA, PIBF1, PIEZO1, PIEZO2, PIGA, PIGB, PIGC, PIGG, PIGH, PIGL, PIGM, PIGN, PIGO, PIGP, PIGQ, PIGS, PIGT, PIGU, PIGV, PIGW, PIGY, PIK3C2A, PIK3CA, PIK3CD, PIK3R1, PIK3R2, PIKFYVE, PINK1, PIP5K1C, PITPNM3, PITX1, PITX2, PITX3, PJVK, PKD1, PKD1L1, PKD2, PKDCC, PKHD1, PKLR, PKP1, PKP2, PLA2G4A, PLA2G6, PLA2G7, PLAA, PLCB1, PLCB4, PLCD1, PLCE1, PLCG2, PLD1, PLEC, PLEKHG5, PLEKHM1, PLG, PLIN1, PLK4, PLN, PLOD1, PLOD2, PLOD3, PLP1, PLPBP, PLS1, PLS3, PLVAP, PMFBP1, PMM2, PMP2, PMP22, PMPCA, PMPCB, PMS2, PMVK, PNKD, PNKP, PNLIP, PNP, PNPLA1, PNPLA2, PNPLA6, PNPLA8, PNPO, PNPT1, POC1A, POC1B, POFUT1, POGLUT1, POGZ, POLA1, POLD1, POLE, POLG, POLG2, POLH, POLR1A, POLR1C, POLR1D, POLR2A, POLR3A, POLR3B, POMC, POMGNT1, POMGNT2, POMK, POMP, POMT1, POMT2, POP1, POR, PORCN, POU1F1, POU3F3, POU3F4, POU4F3, PPA2, PPARG, PPCS, PPIB, PPIP5K2, PPM1D, PPOX, PPP1CB, PPP1R12A, PPP1R15B, PPP2CA, PPP2R1A, PPP2R3C, PPP2R5D, PPP3CA, PPT1, PQBP1, PRCD, PRDM12, PRDM16, PRDM5, PRDM6, PRDM8, PRDX1, PREPL, PRF1, PRG4, PRICKLE1, PRKACG, PRKAG2, PRKAR1A, PRKCD, PRKCG, PRKCSH, PRKD1, PRKDC, PRKG1, PRKN, PRKRA, PRLR, PRMT7, PRNP, PROC, PRODH, PROK2, PROKR2, PROM1, PROP1, PROS1, PRPF3, PRPF31, PRPF4, PRPF6, PRPF8, PRPH2, PRPS1, PRRT2, PRRX1, PRSS1, PRSS12, PRSS56, PRUNE1, PRX, PSAP, PSAT1, PSEN1, PSEN2, PSENEN, PSMB4, PSMB8, PSMC3IP, PSMD12, PSPH, PSTPIP1, PTCH1, PTCH2, PTCHD1, PTDSS1, PTEN, PTF1A, PTGIS, PTH, PTH1R, PTHLH, PTPN11, PTPN14, PTPRC, PTPRF, PTPRO, PTPRQ, PTRH2, PTS, PUF60, PUM1, PURA, PUS1, PUS3, PUS7, PXDN, PYCR1, PYCR2, PYGL, PYGM, PYROXD1, QARS1, QDPR, QRICH1, QRICH2, RAB11B, RAB18, RAB23, RAB27A, RAB28, RAB33B, RAB39B, RAB3GAP1, RAB3GAP2, RAB7A, RAC1, RAC2, RAC3, RAD21, RAD50, RAD51, RAD51C, RAD51D, RAF1, RAG1, RAG2, RAI1, RALGAPA1, RANBP2, RAPSN, RARB, RARS1, RARS2, RASA1, RASGRP1, RASGRP2, RAX, RAX2, RB1, RBBP8, RBCK1, RBM10, RBM20, RBM28, RBM8A, RBP3, RBP4, RBPJ, RCBTB1, RD3, RDH11, RDH12, RDH5, RDX, RECQL4, REEP1, REEP2, REEP6, RELA, RELN, RELT, REN, REPS1, RERE, REST, RET, RETREG1, RFT1, RFWD3, RFX5, RFX6, RFXANK, RFXAP, RGR, RGS9, RGS9BP, RHAG, RHBDF2, RHO, RHOA, RHOBTB2, RIC1, RIMS1, RIN2, RINT1, RIPK1, RIPK4, RIPPLY2, RIT1, RLBP1, RLIM, RMND1, RMRP, RNASEH1, RNASEH2A, RNASEH2B, RNASEH2C, RNASEL, RNASET2, RNF113A, RNF125, RNF13, RNF168, RNF170, RNF213, RNF216, RNF43, RNPC3, RNU4ATAC, ROBO2, ROBO3, ROBO4, ROGDI, ROM1, ROR1, ROR2, RORA, RORB, RORC, RP1, RP1L1, RP2, RP9, RPE65, RPGR, RPGRIP1, RPGRIP1L, RPIA, RPL10, RPL11, RPL13, RPL15, RPL18, RPL21, RPL26, RPL27, RPL35, RPL35A, RPL5, RPS10, RPS15A, RPS17, RPS19, RPS23, RPS24, RPS26, RPS27, RPS28, RPS29, RPS6KA3, RPS7, RPSA, RRAS2, RRM2B, RS1, RSPH1, RSPH3, RSPH4A, RSPH9, RSPO1, RSPO2, RSPO4, RSPRY1, RSRC1, RTEL1, RTN2, RTN4IP1, RTTN, RUBCN, RUNX1, RUNX2, RUSC2, RXYLT1, RYR1, RYR2, S1PR2, SACS, SAG, SALL1, SALL2, SALL4, SAMD9, SAMD9L, SAMHD1, SAR1B, SARS1, SARS2, SASH1, SASS6, SATB2, SBDS, SBF1, SBF2, SC5D, SCAPER, SCARB2, SCARF2, SCN10A, SCN11A, SCN1A, SCN1B, SCN2A, SCN2B, SCN3A, SCN3B, SCN4A, SCN4B, SCN5A, SCN8A, SCN9A, SCNN1A, SCNN1B, SCNN1G, SCO1, SCO2, SCP2, SCYL1, SDCCAG8, SDHA, SDHAF1, SDHAF2, SDHB, SDHC, SDHD, SDR9C7, SEC23A, SEC23B, SEC24D, SEC61A1, SEC63, SECISBP2, SELENBP1, SELENOI, SELENON, SEMA3E, SEMA4A, SEPSECS, SEPTIN9, SERAC1, SERPINA1, SERPINA3, SERPINA6, SERPINB6, SERPINB7, SERPINB8, SERPINC1, SERPIND1, SERPINE1, SERPINF1, SERPINF2, SERPING1, SERPINH1, SERPINI1, SET, SETBP1, SETD1A, SETD2, SETD5, SETX, SF3B4, SFRP4, SFTPA2, SFTPB, SFTPC, SFXN4, SGCA, SGCB, SGCD, SGCE, SGCG, SGMS2, SGO1, SGPL1, SGSH, SH2D1A, SH3BP2, SH3PXD2B, SH3TC2, SHANK2, SHANK3, SHH, SHOC2, SHOX, SHROOM4, SI, SIGMAR1, SIK1, SIL1, SIN3A, SIPA1L3, SIX1, SIX3, SIX5, SIX6, SKI, SKIV2L, SLC10A2, SLC10A7, SLC11A2, SLC12A1, SLC12A3, SLC12A5, SLC12A6, SLC13A3, SLC13A5, SLC16A1, SLC16A12, SLC16A2, SLC17A5, SLC17A8, SLC17A9, SLC18A2, SLC18A3, SLC19A2, SLC19A3, SLC1A1, SLC1A2, SLC1A3, SLC1A4, SLC20A2, SLC22A12, SLC22A5, SLC24A1, SLC24A4, SLC24A5, SLC25A1, SLC25A11, SLC25A12, SLC25A13, SLC25A15, SLC25A19, SLC25A20, SLC25A22, SLC25A24, SLC25A26, SLC25A3, SLC25A32, SLC25A38, SLC25A4, SLC25A42, SLC25A46, SLC26A1, SLC26A2, SLC26A3, SLC26A4, SLC26A5, SLC26A8, SLC27A4, SLC29A3, SLC2A1, SLC2A10, SLC2A2, SLC2A9, SLC30A10, SLC30A2, SLC30A9, SLC33A1, SLC34A1, SLC34A2, SLC34A3, SLC35A1, SLC35A2, SLC35A3, SLC35C1, SLC35D1, SLC37A4, SLC38A8, SLC39A13, SLC39A14, SLC39A4, SLC39A5, SLC39A8, SLC3A1, SLC40A1, SLC44A4, SLC45A1, SLC45A2, SLC46A1, SLC4A1, SLC4A11, SLC4A4, SLC52A2, SLC52A3, SLC5A1, SLC5A2, SLC5A5, SLC5A7, SLC6A1, SLC6A17, SLC6A19, SLC6A2, SLC6A3, SLC6A5, SLC6A8, SLC6A9, SLC7A14, SLC7A7, SLC7A9, SLC9A1, SLC9A3, SLC9A6, SLC9A7, SLCO1B1, SLCO2A1, SLFN14, SLITRK1, SLITRK6, SLURP1, SLX4, SMAD3, SMAD4, SMAD6, SMAD9, SMARCA2, SMARCA4, SMARCAD1, SMARCAL1, SMARCB1, SMARCC2, SMARCD1, SMARCD2, SMARCE1, SMC1A, SMC3, SMCHD1, SMG9, SMN1, SMN2, SMO, SMOC1, SMOC2, SMPD1, SMPD4, SMPX, SMS, SNAP25, SNAP29, SNCA, SNCB, SNIP1, SNRNP200, SNRPB, SNRPE, SNTA1, SNX10, SNX14, SOBP, SOD1, SOHLH1, SON, SOS1, SOS2, SOST, SOX10, SOX11, SOX17, SOX18, SOX2, SOX3, SOX4, SOX5, SOX9, SP110, SP7, SPAG1, SPARC, SPART, SPAST, SPATA5, SPATA7, SPECC1L, SPEF2, SPEG, SPG11, SPG21, SPG7, SPINK1, SPINK5, SPINT2, SPOP, SPR, SPRED1, SPRTN, SPRY4, SPTA1, SPTAN1, SPTB, SPTBN2, SPTBN4, SPTLC1, SPTLC2, SQSTM1, SRC, SRCAP, SRD5A2, SRD5A3, SRP54, SRP72, SRPX2, SRY, SSR4, ST14, ST3GAL3, ST3GAL5, STAC3, STAG1, STAG2, STAG3, STAMBP, STAR, STAT1, STAT2, STAT3, STAT5B, STEAP3, STIL, STIM1, STING1, STK11, STK4, STN1, STRA6, STRADA, STRC, STS, STT3A, STUB1, STX11, STX1B, STXBP1, STXBP2, SUCLA2, SUCLG1, SUFU, SUGCT, SULT2B1, SUMF1, SUN5, SUOX, SURF1, SUZ12, SVBP, SYCE1, SYCP2, SYCP3, SYN1, SYNE1, SYNE2, SYNE4, SYNGAP1, SYNJ1, SYP, SYT1, SYT14, SYT2, SZT2, TAB2, TAC3, TACO1, TACR3, TACSTD2, TAF1, TAF13, TAF2, TAF4B, TAF6, TALDO1, TANGO2, TAP1, TAP2, TAPBP, TAPT1, TARDBP, TARS1, TARS2, TAT, TAZ, TBC1D20, TBC1D23, TBC1D24, TBC1D7, TBC1D8B, TBCD, TBCE, TBCK, TBK1, TBL1X, TBL1XR1, TBR1, TBX1, TBX15, TBX18, TBX19, TBX20, TBX22, TBX3, TBX4, TBX5, TBX6, TBXAS1, TBXT, TCAP, TCF12, TCF20, TCF3, TCF4, TCIRG1, TCN2, TCOF1, TCTEX1D2, TCTN1, TCTN2, TCTN3, TDGF1, TDP1, TDP2, TDRD7, TDRD9, TEAD1, TECPR2, TECR, TECRL, TECTA, TEK, TELO2, TENM3, TENM4, TENT5A, TERC, TERT, TET3, TEX11, TEX14, TEX15, TF, TFAP2A, TFAP2B, TFG, TFR2, TFRC, TG, TGDS, TGFB1, TGFB2, TGFB3, TGFBI, TGFBR1, TGFBR2, TGIF1, TGM1, TGM3, TGM5, TGM6, TH, THAP1, THBD, THG1L, THOC2, THOC6, THPO, THRA, THRB, THSD1, TIA1, TIMM50, TIMM8A, TIMMDC1, TINF2, TJP2, TK2, TKFC, TKT, TLE6, TLK2, TLL1, TMC1, TMC6, TMC8, TMCO1, TMEM106B, TMEM107, TMEM126A, TMEM126B, TMEM127, TMEM132E, TMEM138, TMEM165, TMEM199, TMEM216, TMEM231, TMEM237, TMEM240, TMEM260, TMEM43, TMEM63A, TMEM67, TMEM70, TMEM94, TMEM98, TMIE, TMLHE, TMPRSS15, TMPRSS3, TMPRSS6, TMTC3, TMX2, TNC, TNFAIP3, TNFRSF11A, TNFRSF11B, TNFRSF13B, TNFRSF1A, TNFRSF4, TNFSF11, TNIK, TNNC1, TNNI2, TNNI3, TNNI3K, TNNT1, TNNT2, TNNT3, TNPO3, TNXB, TOE1, TONSL, TOP3A, TOPORS, TOR1A, TOR1AIP1, TP53, TP53RK, TP63, TPI1, TPK1, TPM1, TPM2, TPM3, TPO, TPP1, TPRKB, TPRN, TRAF3IP1, TRAF7, TRAIP, TRAK1, TRAPPC11, TRAPPC12, TRAPPC2, TRAPPC2L, TRAPPC4, TRAPPC6B, TRAPPC9, TRDN, TREM2, TREX1, TRHR, TRIM2, TRIM37, TRIM44, TRIM71, TRIO, TRIOBP, TRIP11, TRIP12, TRIP13, TRIP4, TRIT1, TRMT1, TRMT10A, TRMT10C, TRMT5, TRMU, TRNT1, TRPA1, TRPC3, TRPC6, TRPM1, TRPM4, TRPM6, TRPS1, TRPV3, TRPV4, TRPV6, TRRAP, TSC1, TSC2, TSEN15, TSEN2, TSEN34, TSEN54, TSFM, TSHB, TSHR, TSHZ1, TSPAN12, TSPAN7, TSPEAR, TSPYL1, TSR2, TTBK2, TTC12, TTC19, TTC21A, TTC21B, TTC25, TTC29, TTC37, TTC7A, TTC8, TTI2, TTLL5, TTN, TTPA, TTR, TUB, TUBA1A, TUBA3D, TUBA4A, TUBA8, TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB8, TUBG1, TUBGCP2, TUBGCP4, TUBGCP6, TUFM, TULP1, TUSC3, TWIST1, TWIST2, TWNK, TXN2, TXNL4A, TYK2, TYMP, TYR, TYROBP, TYRP1, UBA1, UBA5, UBAP1, UBE2A, UBE2T, UBE3A, UBE3B, UBIAD1, UBQLN2, UBR1, UBTF, UCHL1, UFC1, UFM1, UFSP2, UGDH, UGP2, UGT1A1, UMOD, UMPS, UNC13D, UNC45B, UNC80, UNG, UPB1, UPF3B, UQCC2, UQCC3, UQCRB, UQCRC2, UQCRFS1, UQCRQ, UROC1, UROD, UROS, USB1, USH1C, USH1G, USH2A, USP18, USP27X, USP45, USP9X, UVSSA, VAC14, VAMP1, VAMP2, VANGL1, VAPB, VARS1, VARS2, VCAN, VCL, VCP, VDR, VEGFC, VHL, VIM, VIPAS39, VKORC1, VLDLR, VMA21, VPS11, VPS13A, VPS13B, VPS13C, VPS13D, VPS33A, VPS33B, VPS37A, VPS45, VPS51, VPS53, VRK1, VSX1, VSX2, VWF, WAC, WARS1, WARS2, WAS, WASF1, WASHC4, WASHC5, WBP2, WDFY3, WDPCP, WDR11, WDR19, WDR26, WDR35, WDR36, WDR37, WDR4, WDR45, WDR45B, WDR62, WDR72, WDR73, WDR81, WEE2, WFS1, WHRN, WIPF1, WNK1, WNK4, WNT1, WNT10A, WNT10B, WNT3, WNT4, WNT5A, WNT7A, WRAP53, WRN, WT1, WWOX, XDH, XIAP, XK, XPA, XPC, XPNPEP3, XPR1, XRCC1, XRCC2, XRCC4, XYLT1, XYLT2, YAP1, YARS1, YARS2, YME1L1, YWHAG, YY1, YY1AP1, ZAP70, ZBTB11, ZBTB16, ZBTB18, ZBTB20, ZBTB24, ZBTB42, ZC3H14, ZC4H2, ZDHHC9, ZEB1, ZEB2, ZFP57, ZFPM2, ZFYVE26, ZIC1, ZIC2, ZIC3, ZMIZ1, ZMPSTE24, ZMYND10, ZMYND11, ZMYND15, ZNF141, ZNF142, ZNF148, ZNF335, ZNF341, ZNF408, ZNF423, ZNF462, ZNF469, ZNF644, ZNF687, ZNF711, ZNF750, ZNHIT3, ZP1, ZP2, ZP3, ZSWIM6